- Synergistic support for bone health
- Promotes healthy calcium metabolism
- Helps maintain cardiovascular health
Vitamin D3 (cholecalciferol) and Vitamin K2-7 (menaquinone) work synergistically to help maintain bone health. Vitamin D3 helps maintain healthy serum calcium levels by promoting intestinal absorption and reducing urinary excretion of calcium. Vitamin K2-7 supports healthy bone mineralization by acting as a cofactor in the carboxylation of osteocalcin, allowing calcium to bind to this protein in the extracellular matrix of bone.
Vitamin K2-7 also supports healthy cardiac and vascular function. This form of Vitamin K concentrates in the tissues of the arteries, where it aids in carboxylation of Matrix Gla Protein to help maintain normal calcium metabolism and support healthy vascular elasticity. Additionally vitamin K2 may help support healthy lipid levels and glucose metabolism.
Although frank vitamin K deficiency is rare, research suggests the Western diet may not contain sufficient Vita-min K2-7 to optimize carboxylation of Gla outside the liver. Higher dietary intakes of K2 have been associated with healthy levels of arterial calcification and elasticity.
Compared to other forms of Vitamin K, Vitamin K2-7 has a longer half-life, resulting in more stable levels in the body. For best absorption of these fat soluble vitamins, take with a mixed meal or some healthy dietary fat.