This product contains BioCell Collagen II, a patented, hydrolyzed and denatured low molecular weight type II collagen. This form of collagen is the most abundant form in the joint matrix. In addition to collagen, BioCell Collagen II provides the combined benefits of hyaluronic acid (HA), depolymerized low molecular weight chondroitin sulfate, glucosamine sulfate, and amino acids including lysine, proline and hydroxyproline. These compounds promote cartilage synthesis and enhance synovial fluid, supporting the composition, integrity and motility of joints. A double blind placebo-controlled study involving 16 individuals supplementing with BioCell Collagen II for 8 weeks, indicated statistically significant support for joint function and comfort. In a peak absorption study, serum levels of HA increased gradually and with statistical significance after BioCell Collagen II supplementation, emphasizing the potential for this compound to provide important connective tissue support. The components of collagen type II also support the elasticity and firmness of skin. Furthermore, HA attracts water, promoting hydration and moisture retention within the dermal matrix. Case reports have suggested that BioCell Collagen II may help rejuvenate skin and modulate the appearance of fine lines and wrinkles.
Pure Encapsulations recommends 2-4 capsules per day, in divided doses, with 8-10 oz water, with meals.