Cats claw, also known as Uncaria tomentosa, has been used traditionally in Peru for over 2,000 years. Alkaloids, phenols,sterols and glycosides comprise some of the naturally occurring constituents of this herb. The effects of these compounds are far- reaching and include support for joint function, gastric and intestinal health, cellular protection andimmune activity. In a 52-week, randomized, double blind trial, cats clawextract promoted joint comfort in volunteers. A 4-week study also suggests that cats claw has the ability to promote joint comfort, in part by maintaininghealthy prostaglandin metabolism. Other mechanisms of action that may account for these effects include protecting from oxidative stress and supporting healthy cytokine production. Studies involving cultured gastric epithelial cells suggest that cats claw may provide important antioxidant protection for gut health. Cats claw alkaloids have been specifically associated with enhancing immune system cell function, including phagocytosis and macrophage activity.Cardiovascular support properties include support for healthy vascular andplatelet function. Preliminary evidence suggests that cats claw may provide protective support for healthy breast cell function. Cats claw may becontraindicated for individuals who are taking blood thinning orantihypertensive medications due to a potential synergistic effect.
Pure Encapsulations recommends 1-6 capsules per day,in divided doses, with meals.