5-HTP is a metabolite of tryptophan and precursor of serotonin and melatonin. Tryptophan—>5-HTP—>serotonin—>melatonin. 5-HTP plays a role in mood, sleep, anxiety, and pain sensation. Our 5-HTP is naturally derived from the seeds of the African plant Griffonia simplicifolia and is combined with activated vitamin B-6 as active P-5-P, an important cofactor in serotonin metabolism. Consult with you physician if using SSRI’s.